VLDLR and ApoER2 are receptors for multiple alphaviruses (Nature)
Abraham Lab
Structural basis for continued antibody evasion by the SARS-CoV-2 receptor binding domain (Science)
Abraham Lab
CYB561A3 is the key lysosomal iron reductase required for Burkitt B-cell growth and survival (blood)
Gewurz Lab
A Bacterial Cell-Based Assay To Study SARS-CoV-2 Protein-Protein Interactions (mBio)
Hochschild Lab
Naive human B cells engage the receptor binding domain of SARS-CoV-2, variants of concern, and related sarbecoviruses (Science Immunology)
Schmidt Lab
Watch: Merck’s Covid pill could transform treatment. Here’s how it works (Stat)
Benjamin Gewurz Quoted
Antibiotic persistence and tolerance: not just one and the same (Current Opinion in Microbiology)
Helaine Lab
Cyclic CMP and cyclic UMP mediate bacterial immunity against phages (Cell)
Kranzusch Lab
Auxiliary interfaces support the evolution of specific toxin-antitoxin pairing (Nature Chemical Biology)
Helaine Lab
Biochemical reconstitution defines new functions for membrane-bound glycosidases in assembly of the bacterial cell wall (PNAS)
Walker Lab
The LpoA activator is required to stimulate the peptidoglycan polymerase activity of its cognate cell wall synthase PBP1a (PNAS)
Bernhardt Lab
Listeria exploits IFITM3 to suppress antibacterial activity in phagocytes (Nature Communications)
Higgins Lab
Evolution-inspired redesign of the LPS receptor caspase-4 into an interleukin-1β–converting enzyme (Science Immunology )
Kagan Lab
Control of gasdermin D oligomerization and pyroptosis by the Ragulator-Rag-mTORC1 pathway (Cell)
Kagan Lab
Epstein-Barr Virus Induced Cytidine Metabolism Roles in Transformed B-Cell Growth and Survival (mBio)
Gewurz Lab
cGAS-like receptors sense RNA and control 3′2′-cGAMP signaling in Drosophila (Nature)
Kranzusch Lab
Polar Growth in Corynebacterium glutamicum Has a Flexible Cell Wall Synthase Requirement (mBio)
Bernhardt Lab
Scientists link genetic makeup of bacteria in the human gut to several human diseases (Harvard Gazette)
Kostic Lab
Reconstruction of ancient microbial genomes from the human gut (Nature )
Kostic Lab
The History of Microbiology - A Personal Interpretation (Annual Review of Microbiology )
Virus-mediated inactivation of anti-apoptotic Bcl-2 family members promotes Gasdermin-E-dependent pyroptosis in barrier epithelial cells (Immunity )
Kagan Lab
Interferon-Independent Restriction of RNA Virus Entry and Replication by a Class of Damage-Associated Molecular Patterns (mBio )
Kagan Lab
SARS-CoV-2 evolution in an immunocompromised host reveals shared neutralization escape mechanisms (Harvard News & Research )
Abraham Lab
SARS-CoV-2 hijacks folate and one-carbon metabolism for viral replication (Nature Communications )
Gewurz Lab
Protein Substrates Engage the Lumen of O-GlcNAc Transferase's Tetratricopeptide Repeat Domain in Different Ways (Biochemistry )
Walker Lab
Deep-sea microbes as tools to refine the rules of innate immune pattern recognition (Science Immunology )
Kagan Lab
Coronavirus-specific antibody cross reactivity in rhesus macaques following SARS-CoV-2 vaccination and infection (Journal of Virology )
Glycoprotein N-linked glycans play a critical role in arenavirus pathogenicity ( PLoS Pathogens )
Abraham Lab
Vaccines can get us to herd immunity, despite the variants ( The Harvard Gazette )
Abraham Lab
Multi-kingdom ecological drivers of microbiota assembly in preterm infants ( Nature )
Rakoff-Nahoum Lab
Toward a comprehensive analysis of posttranscriptional regulatory networks: A new tool for the identification of small RNA regulators of specific mRNAs ( mBio )
Lory Lab
Dissecting serotype-specific contributions to live oral cholera vaccine efficacy ( PNAS )
Waldor Lab
Regulation of host and virus genes by neuronal miR-138 favours herpes simplex virus 1 latency ( Nature Microbiology )
Knipe Lab
Herpes simplex virus 1 manipulates host cell antiviral and proviral DNA damage responses ( mBio )
Knipe Lab
Tripartite Motif 22 (TRIM22) protein restricts herpes simplex virus 1 by epigenetic silencing of viral immediate-early genes ( PLOS Pathogens )
Knipe Lab
Impact of bacterial persisters on their host ( Current Opinion in Microbiology )
Helaine Lab
Functional analyses of epidemic Clostridioides difficile toxin B variants reveal their divergence in utilizing receptors and inducing pathology ( PLoS Pathogens )
Dong Lab
Factors that mold the nuclear landscape of HIV-1 integration ( Nucleic Acids Research )
Engelman Lab
Increased Listeria monocytogenes dissemination and altered population dynamics in Muc2-deficient mice ( Infection and Immunity )
Waldor Lab