April 14, 2021

Interferon-Independent Restriction of RNA Virus Entry and Replication by a Class of Damage-Associated Molecular Patterns
Read More (mBio )
Kagan Lab

 

March 16, 2021

SARS-CoV-2 evolution in an immunocompromised host reveals shared neutralization escape mechanisms
Read More (Harvard News & Research )
Abraham Lab
 

March 15, 2021

SARS-CoV-2 hijacks folate and one-carbon metabolism for viral replication
Read More (Nature Communications )
Gewurz Lab
 

March 15, 2021

Protein Substrates Engage the Lumen of O-GlcNAc Transferase's Tetratricopeptide Repeat Domain in Different Ways
Read More (Biochemistry )
Walker Lab
 

March 15, 2021

Deep-sea microbes as tools to refine the rules of innate immune pattern recognition
Read More (Science Immunology )
Kagan Lab
 

March 11, 2021

Coronavirus-specific antibody cross reactivity in rhesus macaques following SARS-CoV-2 vaccination and infection
Read More (Journal of Virology )
Schmidt Lab
Barouch Lab
 

March 1, 2021

Glycoprotein N-linked glycans play a critical role in arenavirus pathogenicity
Read More ( PLoS Pathogens )
Abraham Lab
 

February 26, 2021

Vaccines can get us to herd immunity, despite the variants
Read More ( The Harvard Gazette )
Abraham Lab
 

February 25, 2021

Multi-kingdom ecological drivers of microbiota assembly in preterm infants
Read More ( Nature )
Rakoff-Nahoum Lab
 

February 24, 2021

Toward a comprehensive analysis of posttranscriptional regulatory networks: A new tool for the identification of small RNA regulators of specific mRNAs
Read More ( mBio )
Lory Lab
 

February 16, 2021

Dissecting serotype-specific contributions to live oral cholera vaccine efficacy
Read More ( PNAS )
Waldor Lab
 

February 11, 2021

Regulation of host and virus genes by neuronal miR-138 favours herpes simplex virus 1 latency
Read More ( Nature Microbiology )
Knipe Lab
 

February 9, 2021

Herpes simplex virus 1 manipulates host cell antiviral and proviral DNA damage responses
Read More ( mBio )
Knipe Lab
 

February 1, 2021

Tripartite Motif 22 (TRIM22) protein restricts herpes simplex virus 1 by epigenetic silencing of viral immediate-early genes
Read More ( PLOS Pathogens )
Knipe Lab
 

February 1, 2021

Impact of bacterial persisters on their host
Read More ( Current Opinion in Microbiology )
Helaine Lab
 

January 29, 2021

Functional analyses of epidemic Clostridioides difficile toxin B variants reveal their divergence in utilizing receptors and inducing pathology
Read More ( PLoS Pathogens )
Dong Lab
 

January 26, 2021

Factors that mold the nuclear landscape of HIV-1 integration
Read More ( Nucleic Acids Research )
Engelman Lab
 

January 11, 2021

Increased Listeria monocytogenes dissemination and altered population dynamics in Muc2-deficient mice
Read More ( Infection and Immunity )
Waldor Lab
 

November 17, 2020

Ensuring vaccine safety
Read More ( Science )
Knipe Lab
 

November 16, 2020

Lipoteichoic acid polymer length is determined by competition between free starter units
Read More ( PNAS )
Walker Lab
 

October 19, 2020

How Coronavirus Drugs Are Helping Patients
Read More ( AARP )
Abraham Lab
 

September 14, 2020

A conserved subcomplex within the bacterial cytokinetic ring activates cell wall synthesis by the FtsW-FtsI synthase
Read More ( PNAS )
Bernhardt Lab
 

September 4, 2020

STING cyclic dinucleotide sensing originated in bacteria
Read More ( Nature )
Kranzusch Lab
 

July 22, 2020

Potent neutralizing antibodies directed to multiple epitopes on SARS-CoV-2 spike.
Read More ( Nature )
Sodroski Lab
 

July 20, 2020

Coronavirus vaccine from Oxford and AstraZeneca shows positive response in early trial
Read More ( CNBC )
Jonathan Abraham quoted
 

June 17, 2020

CBASS immunity uses CARF-related effectors to sense 3'-5'- and 2'-5'-linked cyclic oligonucleotide signals and protect bacteria from phage infection
Read More ( Cell )
Kranzusch Lab
 

June 11, 2020

Slow Receptor Binding of the Noncytopathic HIV-2UC1 Envs Is Balanced by Long-Lived Activation State and Efficient Fusion Activity
Read More ( Cell Reports )
Sodroski Lab
 

May 26, 2020

DNA vaccine protection against SARS-CoV-2 in rhesus macaques
Read More ( Science )
Schmidt Lab
 

May 13, 2020

Massachusetts research consortium (MassCPR) announces funding for projects to combat COVID-19
Read More (  MassCPR )
Abraham Lab Lab
Gehrke Lab
Knipe Lab
 

April 30, 2020

Suzanne Walker Elected to the National Academy of Sciences
Read More ( Harvard News & Research )
Walker Lab
 

April 20, 2020

Structure-Guided Molecular Grafting of a Complex Broadly Neutralizing Viral Epitope
Read More ( ACS Infectious Diseases )
Schmidt Lab
 

April 13, 2020

Despite physical distancing, HMS Quad scientists ramp up efforts to combat COVID-19
Read More ( HMS News & Research )
Schmidt Lab
 
To stem the coronavirus crisis, Harvard Medical School scientists forge ahead on six key fronts

March 31, 2020

Read More ( Ending the Pandemic)
Abraham Lab,  Knipe Lab
 
Global phenotypic profiling identifies a conserved actinobacterial cofactor for a bifunctional PBP-type cell wall synthase

March 16, 2020

Read More ( eLife)
Bernhardt Lab
 
The Tol-Pal system is required for peptidoglycan-cleaving enzymes to complete bacterial cell division

March 11, 2020

Read More ( PNAS)
Bernhardt Lab
 
Cooperating to Combat Coronavirus

February 24, 2020

Read More ( Harvard Magazine)
Knipe Lab
 
Five Questions: A conversation with Ann Hochschild

February 18, 2020

Read More ( Harvard Medicine)
Hochschild Lab
 
Uncovering the activities, biological roles, and regulation of bacterial cell wall hydrolases and tailoring enzymes

January 27, 2020

Read More ( The Journal of biological chemistry)
Walker Lab
 
Research in mice shows antibodies derived from mom’s gut microbes protect newborns from E. coli infection

January 8, 2020

Read More (PNAS)
Bernhardt Lab
 
A broad-spectrum antiviral molecule, QL47, selectively inhibits eukaryotic translation

December 30, 2019

Read More ( The Journal of biological chemistry)
Yang Lab
 
Homeostatic control of cell wall hydrolysis by the WalRK two-component signaling pathway in Bacillus subtilis

December 6, 2019

Read More ( eLife)
Rudner Lab
 
Herpesviral lytic gene functions render the viral genome susceptible to novel editing by CRISPR/Cas9

December 2, 2019

Read More ( HMS News )( eLife)
Knipe Lab

 

Faculty and staff save resources while setting an example for health and wellness

November 12, 2019

Read More ( The path to sustainable commuting)
Jon Beckwith
 
A Quest for Better Vaccines

September 30, 2019

Read More ( Five Questions: A conversation with Darren Higgins)
Higgins Lab
 
The Landscape of Genetic Content in the Gut and Oral Human Microbiome

August 14, 2019

Read More (Cell Host & Microbe)
Kostic Lab
 
Cholera toxin promotes pathogen acquisition of host-derived nutrients

August 2, 2019

Read More (Nature)
Mekalanos Lab
 
A HTRF based competitive binding assay for screening specific inhibitors of HIV-1 capsid assembly targeting the C-terminal domain of capsid

July 2, 2019

Read More (Antiviral Research)
Engelman Lab

 

Epstein-Barr-virus-induced one-carbon metabolism drives B cell transformation

July 2, 2019

Read More (Cell Metabolism)
Gewurz Lab

 

Study finds performance-enhancing bacteria in human microbiome

June 26, 2019

Read More (The Harvard Gazette)
Kostic Lab

 

HCF-1 regulates de novo lipogenesis through a nutrient-sensitive complex with ChREBP

June 26, 2019

Read More (Molecular Cell)
Walker Lab

 

Influenza antigen engineering focuses immune responses to a subdominant but broadly protective viral epitope

May 21, 2019

Read More (Cell Host & Microbe)
Schmidt Lab

 

When we stop thinking about microbes as cells

May 15, 2019

Read More (Journal of Molecular Biology)
Kolter Lab

 

RNA ligands activate the Machupo virus polymerase and guide promoter usage

May 14, 2019

Read More (PNAS)
Whelan Lab

 

Maternal immunization confers protection against neonatal herpes simplex mortality and behavioral morbidity

April 16, 2019

Read More (Science Translational Medicine)
Knipe Lab

 

How Penicillin Acts Like TNT for Bacteria

April 09, 2019

Read More (Howard Hughes Medical Institute)
Bernhardt / Rudner Labs