2024
Identification and characterization of the Bacillus subtilis spore germination protein GerY
(Journal of Bacteriology) Rudner Lab
DMS-MapSeq Analysis of Antisense Oligonucleotide Binding to lncRNA PANDA
(Current Protocols) Rouskin Lab
Animal and bacterial viruses share conserved mechanisms of immune evasion
(Cell) Kranzusch Lab
Adipose tissue–gut microbiome crosstalk in inflammation and thermogenesis
(Trends in Endocrinology & Metabolism) Kostic Lab
The mechanism of peptidoglycan O-acetylation in Gram-negative bacteria typifies bacterial MBOAT-SGNH acyltransferases
(J Biol Chem) Walker Lab
Cytotoxic CD4+ T Cells Are Induced during Infection with Chlamydia trachomatis
(J Immunol) Starnbach Lab
Dissecting host–microbe interactions with modern functional genomics
(Current Opinion in Microbiology) Jost Lab
Viral RNA Interactome: The Ultimate Researcher’s Guide to RNA–Protein Interactions
(Viruses) Rouskin Lab
A prophage competition element protects Salmonella from lysis
(Cell Host & Microbe) Helaine Lab
Untangling the pseudoknots of SARS-CoV-2: Insights into structural heterogeneity and plasticity
(Current Opinion in Structural Biology) Rouskin Lab
Viral DNA polymerase structures reveal mechanisms of antiviral drug resistance.
(Cell) Abraham Lab
Co-ordinated assembly of the multilayered cell envelope of Gram-negative bacteria
(Curr Opin Microbiol) Bernhardt Lab
A coordinated attack by a bacterial secretion system and a small molecule drives prey specificity
(Communications Biology) Mekalanos Lab
Differential Drug Susceptibility across Trichomonasvirus Species Allows for Generation of Varied Isogenic Clones of Trichomonas vaginalis
(Pathogens) Nibert Lab
Structure and assembly of a bacterial gasdermin pore
(Nature) Kranzusch Lab
Tracking the progeny of bacterial persisters using a CRISPR-based genomic recorder
(PNAS) Helaine Lab
Structural basis for VLDLR recognition by eastern equine encephalitis virus
(Nature Comm) Abraham Lab
Identification of a Polypeptide Inhibitor of O-GlcNAc Transferase with Picomolar Affinity
(J Am Chem Soc) Walker Lab
Dissecting OGT's TPR domain to identify determinants of cellular function
(PNAS) Walker Lab
A feedback control mechanism governs the synthesis of lipid-linked precursors of the bacterial cell wall
(Nat Microbiol) Bernhardt Lab
Shifts in receptors during submergence of an encephalitic arbovirus
(Nature) Abraham Lab
Bacillus subtilis uses the SigM signaling pathway to prioritize the use of its lipid carrier for cell wall synthesis
(PLoS Biol) Rudner Lab
FacZ is a GpsB-interacting protein that prevents aberrant division-site placement in Staphylococcus aureus
(Nat Microbiol) Bernhardt and Rudner Labs
Intoxication of antibiotic persisters by host RNS inactivates their efflux machinery during infection
(PLoS Pathog) Helaine Lab
Human otic progenitor cell models of congenital hearing loss reveal potential pathophysiologic mechanisms of Zika virus and cytomegalovirus infections
(mBio) Gehrke Lab
Sp1 facilitates continued HSV-1 gene expression in the absence of key viral transactivators
(mBio) Knipe Lab
Inhibition of human immunodeficiency virus (HIV-1) infectivity by expression of poorly or broadly neutralizing antibodies against Env in virus-producing cells
(Journal of Virology) Sodroski Lab
Tracing the evolutionary origins of antiviral immunity
(PLOS Biology) Kranzusch Lab
Synthesis of lipid-linked precursors of the bacterial cell wall is governed by a feedback control mechanism in Pseudomonas aeruginosa
(Nature Microbiology) Bernhardt Lab
Systematic analysis of nonprogrammed frameshift suppression in E. coli via translational tiling proteomics
(PNAS) Hochschild Lab
Heterologous Sarbecovirus Receptor Binding Domains as Scaffolds for SARS-CoV-2 Receptor Binding Motif Presentation
(ACS infect Dis) Schmidt Lab
SpoVAF and FigP assemble into oligomeric ion channels that enhance spore germination
(Genes Dev.) Rudner Lab
Structural basis of Gabija anti-phage defence and viral immune evasion
(Nature) Kranzusch Lab